Aerobic Exercise-Induced TGF-β Receptor Reprogramming Disrupts Neutrophil-Microglia Crosstalk to Attenuate Early Brain Injury after Subarachnoid Hemorrhage.

Research (Wash D C) · 2026 · PMC13216690 · PMID 42221302

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did not reach statistical significanceno p-value reported

In contrast, Lrg1-ko neutrophils significantly attenuated these pro-inflammatory responses in wt-microglia and partially restored anti-inflammatory signaling and Smad2/3 phosphorylation, though some changes did not reach statistical significance.

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