Intracardiac Versus Transesophageal Echocardiography for Left Atrial Appendage Occlusion: A Meta-Analysis.

51 , 52 Encouragingly, this risk appears to be modifiable by experience; both Ferro et al (2023) and Alkhouli et al (2025) observed a reduction in intervention-requiring PE rates as operator volume increased, though this trend did not reach statistical significance in the latter analysis, highlighting the potential impact of the learning curve. 21 , 22 Similarly, we observed that ICE guidance was consistently associated with a higher rate of residual iASD.

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