Perioperative alvimopan versus no alvimopan after elective minimally invasive colorectal resection within enhanced recovery pathways: a GRADE-assessed systematic review and meta-analysis.

BMC Surg · 2026 · PMC13220404 · PMID 42168954

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closest p

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did not reach statistical significanceno p-value reported

However, the result did not reach statistical significance because the confidence interval crossed the null value and the overall P-value was 0.06.

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a numerical trendno p-value reported

In contrast, length of stay and readmission were not statistically significant in the primary pooled analyses, although length of stay showed a numerical trend favoring alvimopan.

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