Meanwhile, 50 of 200 genes belonging to “oxidative phosphorylation” (M5936), strongly enriched in the in vivo situation, were significantly regulated in vitro, yet this enrichment failed to reach statistical significance given the overall large number of genes regulated by IFN-γ in MDMs (fig.
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A STAT1/ETC/GBP1 axis represents a potential therapeutic target for noncommunicable granulomatous skin disease.
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