Successful Implementation of a Nurse-Led Daily Spontaneous Awakening Trial Within a Modified Extubation Protocol: A Before-and-After Study.

Cureus · 2026 · PMC13221903 · PMID 42220863

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did not reach statistical significanceno p-value reported

Fourth, the sample size may have been insufficient to detect clinically meaningful differences in outcomes, such as re-intubation rate and PERF, as suggested by trends that did not reach statistical significance.

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