Effect of multimodal therapy in the treatment of adenocarcinoma of the esophagus and gastroesophageal junction : a population-based analysis from the German Clinical Cancer Registry Group.

Langenbecks Arch Surg · 2026 · PMC13222164 · PMID 42215752

Europe PMC DOI

hedged sentences

0.0640

closest p · 1.3× alpha

0.0640

boldest claim

The sentences

did not reach statistical significancep = 0.064so close (0.05 < p ≤ 0.1)

Although perioperative chemotherapy tended to be associated with longer OS, it did not reach statistical significance when compared to neoadjuvant radiochemotherapy + surgery ( p = 0.064).

also in 111,027 other papers

an obvious trendno p-value reported

Despite an obvious trend toward perioperative therapy, there was no statistical superiority between perioperative chemotherapy or neoadjuvant radiochemotherapy.

also in 1,006 other papers

marginally non-significantno p-value reported

This marginally non-significant result in favour for perioperative Chemotherapy could be due to the fact that there was no differentiation between the two perioperative chemotherapy protocols of ECF and FLOT in the presented study.

also in 1,493 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.