Barely Significant
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Genetic inference of the etiological crosstalk between primary glaucomas and retinal vascular occlusions.

Adv Ophthalmol Pract Res · 2026 · PMC13223934 · PMID 42232215

3
hedged sentences
0.0540
closest p · 1.1× alpha
0.0540
boldest claim

The sentences

borderline significanceP =0.054so close (0.05 < p ≤ 0.1)
53 We observed a latent connection between RVO and PACG in this MR study, with a borderline significance of P =0.054.

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did not reach statistical significanceP =0.054so close (0.05 < p ≤ 0.1)
In the reverse direction, RVO (central or branch) was associated with an OR of 1.258 for primary angle-closure glaucoma (PACG); however, this association did not reach statistical significance (95% CI: 0.996-1.589, P =0.054).

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may be significantno p-value reported
23 Even a slight increase in IOP may be significant enough to jeopardize ocular perfusion, leading to subsequent venous slowing or stasis53. 3 Therefore, elevated IOP and excessive IOP fluctuation in POAG may further interact with systemic hemodynamic disturbances, exerting a detrimental impact on RVO pathogenesis. 24 Together, according to Virchow'

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.