Life satisfaction mediates advanced maternal age at childbirth and frailty across cohorts.

iScience · 2026 · PMC13223979 · PMID 42231967

Europe PMC DOI

hedged sentence

0.0630

closest p · 1.3× alpha

0.0630

boldest claim

The sentences

did not reach statistical significancep = 0.063so close (0.05 < p ≤ 0.1)

In HRS, the point estimate was in the same direction but did not reach statistical significance (HR: 1.10, 95% CI: 0.99–1.22; p = 0.063).

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