Salivary cortisol dynamics and their relationship with sleep and mental well-being in adults receiving a phospholipid-based <i>Melissa officinalis</i> supplement: a secondary analysis in a subpopulation.

While the aggregated daily mean changes from week 0 to week 1 did not reach statistical significance (95% CI: −0.021 to 0.004, P > 0.05), a significant reduction was already detectable at the 08:00 am time-point after only 1 week of supplementation (95% CI: −0.015 to 0.0009, P < 0.01), as shown in Table 3 .

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