Predictive value of the C-reactive protein-to-lymphocyte ratio for prognosis in heart failure patients with acute kidney injury.

Front Physiol · 2026 · PMC13225966 · PMID 42239670

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0670

boldest claim

The sentences

borderline significanceP = 0.06so close (0.05 < p ≤ 0.1)

In terms of diabetes status, the highest CLR group (CLR_4 group = 4) was significantly linked to increased risk in both diabetic and non-diabetic groups, though non-diabetic patients showed borderline significance for CLR_4 group = 2 (P = 0.06).

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a trend towards significanceP = 0.067so close (0.05 < p ≤ 0.1)

The examination of subgroup variances revealed gender-specific risks; men in the CLR_4 group = 3 faced a notable risk with an HR of 3.61 (P = 0.021), while women showed a trend towards significance at this level (P = 0.067).

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highly significantno p-value reported

Although the HRs for Q2 and Q3 did not reach statistical significance in Model 3, the P for trend across quartiles remained highly significant (< 0.001).

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did not reach statistical significanceno p-value reported

Similar trends were observed for 30-day mortality (Q4: 4.32 [2.19–8.53]; P-trend < 0.001), although the HRs for Q2 and Q3 did not reach statistical significance.

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