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Prognostic heterogeneity in ASXL1-mutated AML and refinement by an immunophenotype-based score.

Front Oncol · 2026 · PMC13225974 · PMID 42239898

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a positive trendno p-value reported
Integrated Discrimination Improvement (IDI) and Net Reclassification Index (NRI) analyses demonstrated a positive trend toward enhanced risk discrimination, although statistical significance was not reached ( Figure 4E ).

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While cytarabine and venetoclax did not reach statistical significance, the overall distribution trended toward increased susceptibility among High-Score patients.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.