Pathway activity scores showed a trend toward downregulation of the androgen pathway, which is closely linked to lipid metabolism, in rAAV2- and rAAV9-CMV-EGFP-treated males and rAAV9-CMV-EGFP-treated females (Fig. 3f ).
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Spatial transcriptomics and single-nucleus RNA sequencing reveal rAAV2- and rAAV9-specific transduction signatures in the mouse liver.
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