Taliglucerase Alfa Reduces Amyloid-β Burden by Restoring Autophagic Pathways in a Neuronal Model of Alzheimer's Disease.

After 32 h of exposure to 5 μM oAβ 1−42 , a significant elevation was observed in monomeric Aβ (4.5 kDa) ( p = 0.0038), while the increase in low molecular weight (LMW) Aβ forms—tetramers, trimers, and dimers—did not reach statistical significance ( p = 0.0685; Fig. 2 a, b).

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