Low Frequency of Pathogenic Variants in BRCA1 Exons 11/20 and BRCA2 Exon 11 Suggests Divergent Mutational Hotspots in Sudanese Breast Cancer Patients: A Case-Control Study.

Breast Cancer (Auckl) · 2026 · PMC13227026 · PMID 42238800

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hedged sentences

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantp = 0.001actually significant

This distribution was highly significant (p = 0.001), confirming a strong predilection for higher-grade tumors within the IDC subtype.

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did not reach statistical significanceno p-value reported

Variant presence was significantly associated with Jaalia ethnicity (P = 0.047) and observed exclusively in IDC cases, though these associations did not reach statistical significance for tumor characteristics.

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