Potent Cytotoxic Tumor-Infiltrating Lymphocytes Can Be Generated from Immune-Excluded Chondrosarcomas Using Regulatable Membrane-Bound IL15.

We have also profiled the REP TIL with more in-depth activation/exhaustion markers and found that cytoTIL15 cells showed a trend toward higher activation marker expression, including CD25 and CD27, and a lower PD-1 expression indicating lower exhaustion profile ( Fig. 4E ; Supplementary Fig.

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