Lacticaseibacillus paracasei 36 attenuates D-GalN/LPS-induced acute liver injury in mice via suppressing the TLR4/NF-κB/MAPK pathway and NLRP3 inflammasome activation through modulating the intestinal microbiota.

J Adv Res · 2026 · PMC13227168 · PMID 41775324

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did not reach statistical significanceno p-value reported

In addition to the statistically significant changes, we observed modest upward trends in IL-10 and IL-17A levels in the LP36 group compared with Control, and in the LP36 + D-GalN/LPS group compared with D-GalN/LPS, although these differences did not reach statistical significance.

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