Genetic manipulation of OGT enhances NK cell-mediated cytotoxicity in tumor immunity.

J Adv Res · 2026 · PMC13227225 · PMID 40914422

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Under basal conditions, LRPPRC displayed strong association with mitochondrial transcripts, which was substantially reduced upon treatment with OSMI-1, an inhibitor of global O-GlcNAcylation, and showed a trend toward enhancement with Thiamet G treatment ( Fig.

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