NT-proBNP was numerically associated with outcome but did not reach statistical significance [HR 1.28 (95% CI 0.96 1.71); P = .10].
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Novel biomarkers distinguish heart failure with preserved vs reduced ejection fraction.
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MYBPC3 [HR 1.62 (95% CI 0.99–2.64); P = .06] remained borderline significant in the adjusted model ( Figure 2 ).