Barely Significant
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Novel biomarkers distinguish heart failure with preserved vs reduced ejection fraction.

ESC Heart Fail · 2026 · PMC13228998 · PMID 41711204

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hedged sentences
0.1000
closest p · 2.0× alpha
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boldest claim

The sentences

did not reach statistical significanceP = .10so close (0.05 < p ≤ 0.1)
NT-proBNP was numerically associated with outcome but did not reach statistical significance [HR 1.28 (95% CI 0.96 1.71); P = .10].

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borderline significantno p-value reported
MYBPC3 [HR 1.62 (95% CI 0.99–2.64); P = .06] remained borderline significant in the adjusted model ( Figure 2 ).

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