Association between potentially inappropriate medications and 30-day outcomes among hospitalized older adults with reduced physiologic reserve: a retrospective cohort study.

Front Pharmacol · 2026 · PMC13229643 · PMID 42244878

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0.1600

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0.1600

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did not reach statistical significanceP = 0.16not close (p > 0.1)

Multivariable Cox regression analysis in the total population revealed that PIM use was associated with a trend toward an increased risk of the 30-day composite outcome, although this association did not reach statistical significance after adjusting for potential confounders (adjusted HR [AHR] 1.22, 95% CI 0.92–1.62, P = 0.16; Table 3 ).

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