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An anoikis-related gene signature predicts prognosis and immunotherapy response, and identifies CCAR2 as a therapeutic target in triple-negative breast cancer.

Front Immunol · 2026 · PMC13229996 · PMID 42245636

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The high-risk group showed a trend toward a higher predicted non-response rate based on the TIDE algorithm, suggesting a potentially poorer response to immunotherapy that warrants further investigation ( Figure 2I ).

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