NKX2-1 regulates cell survival, maturation, and DNAdamage responses as a cofactor of RUNX1 in T-cell acute lymphoblastic leukemia.

Haematologica · 2026 · PMC13231096 · PMID 41504233

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Interestingly, drug treatments on ex vivo cultured PDX samples also showed a trend towards more etoposide resistance in NKX2-1 positive samples ( Figure 4G , Online Supplementary Figure S13 ).

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