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Tfam-mediated metabolic perturbation in RORγt<sup>+</sup> lymphocytes impacts intestinal tissue homeostasis and promotes GATA3<sup>+</sup>RORγt<sup>+</sup> innate lymphoid cells.

Cell Rep · 2026 · PMC13232894 · PMID 41678335

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showed a trendno p-value reported
Of note, the absolute number of GATA3 + RORγt + ILCs showed a trend of increase ( Figures 3C and 3F ) in HFD-fed Tfam f/f Rorc-cre mice compared to their littermate controls but without statistical significance.

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