Causal association and molecular mechanisms of periodontal disease and muscle wasting and atrophy: Mendelian randomization and bioinformatics analysis.

Front Genet · 2026 · PMC13233056 · PMID 42245403

Europe PMC DOI

hedged sentence

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

did not reach statistical significanceP > 0.05actually significant

The other MR methods (MR-Egger, weighted median, simple mode, and weighted mode) showed directionally consistent effects but with smaller effect estimates and did not reach statistical significance (all P > 0.05).

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