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Serum uric acid levels and cardiorenal complication prevalence in hypertensive patients before and after the COVID-19 pandemic: a retrospective cross-sectional study from a tertiary traditional Chinese medicine hospital.

Front Endocrinol (Lausanne) · 2026 · PMC13233390 · PMID 42255435

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In the pre-pandemic period, hyperuricemia was independently associated with higher odds of any cardiorenal complication (OR = 1.70, 95% CI: 1.27–2.29; P < 0.001), CKD (OR = 1.61, 95% CI: 1.16–2.24; P = 0.005), and heart failure (OR = 1.45, 95% CI: 1.02–2.06; P = 0.040), while the associations with stroke (OR = 1.20, 95% CI: 0.79–1.83; P = 0.395) and AF (OR = 1.63, 95% CI: 0.94–2.85; P = 0.081) did not reach statistical significance.

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