Severe hepatitis flares after antiviral withdrawal in chronic hepatitis B with lymphoma: Impact of rituximab.

JHEP Rep · 2026 · PMC13233736 · PMID 42019867

Europe PMC DOI

hedged sentences

0.0690

closest p · 1.4× alpha

0.2120

boldest claim

The sentences

borderline significancep = 0.069so close (0.05 < p ≤ 0.1)

Baseline HBV DNA level ≥4 log 10 IU/ml showed borderline significance (aHR: 1.973, 95% CI: 0.949–4.104, p = 0.069).

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did not reach statistical significancep = 0.212not close (p > 0.1)

Competing-risk analyses treating death as a competing event yielded consistent point estimates, although the between-group difference did not reach statistical significance (2-year CR: 34% vs. 21%, Gray’s p = 0.212; Table S4 ).

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