Barely Significant
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Characterizing symptom burden in knee osteoarthritis: the predominant role of Kellgren-Lawrence grade 4 in functional decline and pain severity.

Rheumatol Int · 2026 · PMC13233923 · PMID 42234140

Europe PMCDOI
1
hedged sentence
0.0010
closest p · 0.0× alpha
0.0010
boldest claim

The sentences

did not reach statistical significancep < 0.001actually significant
borderline significancep = 0.055so close (0.05 < p ≤ 0.1)
Significant differences were observed between Grade 2 and Grade 4 in VAS ( p = 0.013), ICOAP-constant pain score ( p = 0.041), ICOAP-total score ( p = 0.047), TUG ( p = 0.025), and KOS-ADLS ( p = 0.055, borderline significance), while quadriceps muscle strength of the affected knee did not reach statistical significance in this comparison ( p < 0.001 indicates strong significance depending on direction) (Table 3 ).

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