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Neural correlates of altered interoception in depressive and anxiety disorders: a systematic review and meta-analysis.

Eur Arch Psychiatry Clin Neurosci · 2026 · PMC13233944 · PMID 41653309

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Notably, while this relationship was suggested by the qualitative synthesis, it did not reach statistical significance in the meta-analysis, likely due to the use of heterogeneous task design (i.e. the use of respiration and drug intervention design), greater diagnosis variety (i.e. examining panic disorder, social anxiety disorder, and generalized anxiety disorder), and overall fewer anxiety studies.

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