Exploring the impact of collagen-I genetic variants on intestinal structure and gut microbiota in mouse models of osteogenesis imperfecta.

Sci Rep · 2026 · PMC13234298 · PMID 41942702

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

a decreasing trendp = 0.08so close (0.05 < p ≤ 0.1)

In Oim mice, Col1a2 expression was significantly lower in males and showed a decreasing trend in females ( p = 0.08) compared to sex-matched WT (Fig. 3 B).

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did not reach statistical significanceno p-value reported

Male Oim mice demonstrated a more prominent increase in gut permeability compared to Jrt mice, while in female mice similar trend was noted but did not reach statistical significance.

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