Association between intraoperative decentration and corneal higher-order aberrations in lenticule extraction surgery.

BMC Ophthalmol · 2026 · PMC13237933 · PMID 42026519

Europe PMC DOI

hedged sentences

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

did not reach statistical significanceP = 0.057so close (0.05 < p ≤ 0.1)

Beyond the breakpoint (232 μm), the slope increased by an additional 0.00083, indicating a steeper trend; although this did not reach statistical significance at the conventional 0.05 level, the association showed a trend toward significance ( P = 0.057), suggesting that greater decentration beyond the threshold may be associated with increased induction of HOAs (Fig. 1 ).

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marginal significanceP = 0.057so close (0.05 < p ≤ 0.1)

While the piecewise regression identified a breakpoint at 232.5μm, the change in the slope of HOA induction beyond this point showed marginal significance (P = 0.057).

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highly significantno p-value reported

However, the t-test results demonstrated a highly significant difference in the mean induced HOAs between the two groups divided by this threshold.

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