While most subgroups displayed comparable symptom duration, DPR, and education levels, S3 patients were the youngest cohort, exhibiting the lowest median age at the first visit (56 years old) and median age at onset (54 years old), although these differences did not reach statistical significance compared with others.
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Data-driven subtyping and staging of ALS: A multicenter, longitudinal, deformation-based morphometry study.
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