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Ex vivo comparison of ACU193 and lecanemab reveals binding differences in mouse brain.

Alzheimers Dement · 2026 · PMC13239446 · PMID 42222928

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showed a trendno p-value reported
In the cortex, fixation had little effect on vascular labeling by the mAbs, but AMG and pan‐Aβ showed a trend toward reduced labeling with longer fixation, suggesting a modest overall reduction in vascular Aβ detection.

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