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Prognostic Nomogram for Ovarian Cancer Patients on First-Line Maintenance Therapy With PARP Inhibitors: A Retrospective Cohort Study.

Cancer Med · 2026 · PMC13239840 · PMID 42169627

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By analyzing the clinical data of 30 patients with BRCA wild‐type recurrence, multivariate Cox regression analysis showed that platinum‐based chemotherapy remained the key factor for prolonging TTSP (Figure 5D ), whereas a PARPi duration longer than 12 months again showed a trend towards a shorter TTSP duration. 4 Discussion The approval of olaparib for patients with BRCA‐mutated advanced OC has catalyzed the rapid development of PARPis and the expansion of their indications.

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