Critical role of keratinocytes and protease-activated receptor 2 in secondary lymphedema development.

Clin Transl Med · 2026 · PMC13239967 · PMID 42226615

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0.0760

closest p · 1.5× alpha

0.0760

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showed a trendp = .076so close (0.05 < p ≤ 0.1)

However, at the population level, the mean percentage of F2RL1‐positive keratinocytes showed a trend towards reduction in lymphedematous skin (41.6% normal vs. 36.4% LE, paired t ‐test, p = .076) (Figure 1H,I ).

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