Imperatorin ameliorates myocardial ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress-mediated apoptosis via the PI3K/AKT/Nrf2 pathway.

J Cell Commun Signal · 2026 · PMC13240353 · PMID 42256532

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After administration of IMP, the green fluorescence intensity in the cells decreased to varying degrees (Figure 2D, E ), indicating that IMP showed a trend toward reducing the increase of Ca 2+ concentration in the H9c2 cytoplasm induced by H/R.

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