Genetic association and computational analysis of CYP2R1 gene polymorphisms rs2060793 and rs12794714 with vitamin D deficiency and acute myocardial infarction in the Bangladeshi population: A case control study.

Highly significant difference (p-value = 0.0076) found among the study subjects’ genotypic arrangement by performing Chi-square test.

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However, this variation in allele frequencies did not reach statistical significance (p = 0.0821), suggesting no strong association with disease status in the studied population.

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Although the difference in circulating vitamin D levels across rs2060793 genotypes did not reach statistical significance, a decreasing trend was observed.

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However, this trend did not reach statistical significance (p = 0.0819), though it approached borderline significance.

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Similarly, LDL levels showed mean ± SEM values of 87.22 ± 3.72 mg/dL (CC), 88.94 ± 2.96 mg/dL (CT), and 90.04 ± 5.28 mg/dL (TT), even though there is an increasing trend but the variation between groups is not significant (p = 0.8701).

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