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Comparative Analysis of Dual-miRNA Mediated Stimulation of Nucleus Pulposus and Bone Marrow Derived Stem Cells for Intervertebral Disc Repair.

JOR Spine · 2026 · PMC13241378 · PMID 42253284

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0.1025
closest p · 2.0× alpha
0.1025
boldest claim

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showed a trendp = 0.1025not close (p > 0.1)
miRNA‐BMSCs exhibited increased expression of the more fibrotic collagen type I compared with NT controls (Figure 5D,E , p = 0.033), while collagen type II showed a trend towards higher expression in the transfected BMSC group (Figure 5F,G , p = 0.1025). 3.6. miRNA Transfection Induced Differential Catabolic and Inflammatory Responses Between Cell Types Restoring homeostatic balance in the degenerated IVD requires the suppression of catabolic and inflammatory mediators.

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