Optimization of a parallel CAR for B-cell lymphoma via ITAM attenuation and target specificity validation.

Clin Exp Immunol · 2026 · PMC13242215 · PMID 42200445

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did not reach statistical significanceno p-value reported

The human CD45% was significantly higher in spleen, bone marrow, and peripheral blood of pCAR-Y05(1XX)/F CAR T-cell treated mice, although differences in liver did not reach statistical significance ( Fig. 6a ).

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