Total Joint Arthroplasty in Ehlers-Danlos Syndrome Is Associated with Increased Instability and Revision: A Systematic Review and Meta-analysis.

Indian J Orthop · 2026 · PMC13242344 · PMID 42261432

Europe PMC DOI

hedged sentence

0.0650

closest p · 1.3× alpha

0.0650

boldest claim

The sentences

did not reach statistical significancep = 0.065so close (0.05 < p ≤ 0.1)

Meta-analysis suggested a higher risk of aseptic loosening in the EDS group, although this did not reach statistical significance (RR 2.02, 95% CI 0.94–4.32, p = 0.065; I 2 = 0.7%) (Fig. 5 ).

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