Social vulnerability shapes deep clinical phenotypes and brain health in aging and dementia across Latin America.

Alzheimers Dement · 2026 · PMC13242611 · PMID 42251497

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0710

boldest claim

The sentences

marginally significantp = 0.06so close (0.05 < p ≤ 0.1)

Post hoc comparisons revealed higher anxiety among high‐vulnerability participants in AD ( t (3933) = 4.49, p < 0.001, d = 0.26), whereas differences in CUs were marginally significant ( t (3933) = 2.76, p = 0.06, d = 0.12) and non‐significant in FTLD ( t (3933) = 2.030, p < 0.001, d = 0.192).

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did not reach statistical significancep = 0.071so close (0.05 < p ≤ 0.1)

Conversely, in the low vulnerability group, this difference did not reach statistical significance ( t (3933) = 2.200, p = 0.071, d = 0.108). 3.4.

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