Effect of vaginal estrogen supplementation for luteal phase support in the GnRH antagonist protocol on pregnancy outcomes for IVF/ICSI cycles: a randomized controlled trial.

Hum Reprod Open · 2026 · PMC13243313 · PMID 42266463

Europe PMC DOI

hedged sentence

0.0910

closest p · 1.8× alpha

0.0910

boldest claim

The sentences

did not reach statistical significanceP = 0.091so close (0.05 < p ≤ 0.1)

According to the ITT analysis, the ongoing pregnancy rate was higher in the E + P group (46.33%, 120/259) compared to the P group (39.00%, 101/259), although this difference did not reach statistical significance (RR 1.19, 95% CI: 0.97–1.45; P = 0.091).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.