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Molecular and cellular adaptations to extended hypothermic oxygenated perfusion in donation-after-circulatory-death hearts in a porcine model.

Front Cardiovasc Med · 2026 · PMC13243425 · PMID 42267099

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KEGG pathway enrichment analyses of upregulated DEGs in Group 1 hearts show that mostly inflammation-related signaling reached statistical significance (FDR < 0.01) while KEGG pathways for downregulated DEGs did not reach statistical significance ( Figure 4C ).

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