Novel therapeutic cav1.3-C-terminus normalizes L-type calcium current and ejection fraction in ischemia-induced murine heart failure.

Biochem Biophys Res Commun · 2025 · PMC13244280 · PMID 40782450

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did not reach statistical significanceno p-value reported

Interestingly, the Cav1.2 gene ( CACN1C ; α 1C subunit of the L-type calcium channel) was downregulated by −0.5 Log2-fold but did not reach statistical significance, confirming that the Cav1.3 C-terminus does not affect Cav1.2 gene expression.

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