Integrative bioinformatics, network toxicology, and molecular docking elucidate molecular mechanisms of ATBC-induced sarcoma progression with experimental validation.

BMC Pharmacol Toxicol · 2026 · PMC13245103 · PMID 42032714

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did not reach statistical significanceno p-value reported

Although the mRNA changes of SIRT1, NFKB1, and PTGS2 did not reach statistical significance in the survival analysis, their expression trends aligned with the direction of clinical outcomes, suggesting that they may play auxiliary roles in the ATBC toxicity network.

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