Effectiveness of manual therapy on physical and mental health promotion in adults: a systematic review and meta-analysis.

According to the meta-analysis, participants receiving manual therapy had significantly lower systolic blood pressure than those in the control group [MD = −3.91 (95%CI −4.63 to −3.18) P < 0.00001, I 2 = 32%] ( Figure 5 ), whereas diastolic blood pressure was lower in the manual therapy group but did not reach statistical significance Amended to: [MD = −0.67 (95%CI −2.51 to 1.18) P = 0.48, I 2 = 71%] ( Figure 6 ).

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