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Atherogenic index of plasma and severe headaches or migraines risk in US adults: a population-based cross-sectional analysis from NHANES 1999-2004.

Front Neurol · 2026 · PMC13246651 · PMID 42273032

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However, the test for non-linearity did not reach statistical significance ( P non − linear = 0.147), suggesting that while risk generally increases with AIP, the dose-response curve may exhibit instability or follow a modest linear trend rather than a definitive non-linear trajectory ( Figure 2 ). 3.3 Subgroup analyses Subgroup analyses revealed consistent positive associations between AIP and severe headaches or migraines across multiple strata.

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