Mapping the Neurovascular Unit Genetic Architecture of Early-Onset Ischemic Stroke: A Single-Cell Causal Framework for Target Discovery and Therapeutic Translation.

Cell Mol Neurobiol · 2026 · PMC13247016 · PMID 42033474

Europe PMC DOI

hedged sentence

0.1600

closest p · 3.2× alpha

0.1600

boldest claim

The sentences

did not reach statistical significanceP = 0.16not close (p > 0.1)

By contrast, ANXA11 expression in astrocytes exhibited a protective trend (OR = 0.88, 95% CI = 0.74–1.05) but did not reach statistical significance ( P = 0.16) (Fig. 4 ).

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