Foslevodopa-Foscarbidopa subcutaneous infusion in Parkinson's disease: a cross-cultural/cross-racial international multicentre comparative tolerability study (CRIM-FOS study).

Sci Rep · 2026 · PMC13247094 · PMID 41991639

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did not reach statistical significanceno p-value reported

However, the changes observed from baseline to 6 months and from baseline to 12 months did not reach statistical significance.

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highly significantno p-value reported

The main effect of time was highly significant for caregiver burden Bonferroni-adjusted pairwise comparisons revealed significant reductions in caregiver burden from baseline to 6 months (mean difference = 18.77, p < .001), from baseline to 12 months (mean difference = 22.09, p < .001), and from 6 to 12 months (mean difference = 3.31, p < .001).

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