Integration of retinal layer thinning into NEDA-3 predicts disability progression in multiple sclerosis.

J Neurol · 2026 · PMC13249778 · PMID 42262609

Europe PMC DOI

hedged sentences

0.0770

closest p · 1.5× alpha

0.0770

boldest claim

The sentences

showed a trendp = 0.077so close (0.05 < p ≤ 0.1)

EDA-3 showed a trend for higher risk of disability progression in the LE-DMT subgroup (aHR = 2.01, 95% LL-CI = 0.90, p = 0.077), while no such association was evident in the HE-DMT subgroup (aHR = 0.59, 95% UL-CI = 3.59, p = 0.317, Fig. 3 C).

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an overall trendno p-value reported

OCT worsening at 12 months was associated with an overall trend to more disability progression events, both in NEDA-3 and EDA-3 groups (Suppl.

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