Barely Significant
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IVUS-Guided Versus Angiography-Guided PCI for Unprotected Left Main Coronary Artery Disease: A Systematic Review, Meta-Analysis, and GRADE Assessment of Randomized Trials.

Clin Cardiol · 2026 · PMC13250836 · PMID 42267704

1
hedged sentence
0.1700
closest p · 3.4× alpha
0.1700
boldest claim

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did not reach statistical significancep = 0.17not close (p > 0.1)
3.4 Primary Outcomes For the primary outcomes, pooled analysis showed that IVUS‐guided left main coronary artery intervention was associated with a numerically lower risk of all‐cause death compared with conventional angiography, although this did not reach statistical significance (RR = 0.64, 95% CI: 0.34–1.21; p = 0.17), with no heterogeneity across studies ( I 2 = 5.8%) (Figure 3A ).

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