IgA anti-CD74 autoantibodies are associated with treatment escalation in peripheral psoriatic arthritis.

Front Immunol · 2026 · PMC13250937 · PMID 42282961

Europe PMC DOI

hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

did not reach statistical significancep = 0.053so close (0.05 < p ≤ 0.1)

When analyzed by treatment class (data were available for 126 patients), anti-CD74 levels were numerically higher in csDMARD-treated patients (n = 106) compared to untreated individuals (n = 20) (median 12.5 vs 10.5 U/mL); however, this difference did not reach statistical significance (p = 0.053).

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